RT Journal Article SR Electronic A1 Canavan, Neil T1 Development of Deep Brain Stimulation for the Treatment of Resistant Depression JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 3 SP 7 OP 8 DO 10.1177/155989770800800302 UL http://mdc.sagepub.com/content/8/3/7.abstract AB Although a variety of treatments for major depression are available, less than 40% of patients achieve remission with their first treatment [Rush AJ et al. Am J Psychiatry 2006], and approximately 10% becomes treatment-resistant over time. New treatments are needed for patients who remain depressed despite having tried all available therapies. This article discusses the use of deep brain stimulation as a treatment for patients with chronic, treatment-resistant depression who have failed all other therapies.