PT - JOURNAL ARTICLE AU - Canavan, Neil ED - DeFronzo, Ralph A. TI - Insulin Resistance as a Major Risk Factor for Cardiovascular Disease DP - 2008 Nov 01 TA - MD Conference Express PG - 32--33 VI - 8 IP - 7 4099 - http://mdc.sagepub.com/content/8/7/32.short 4100 - http://mdc.sagepub.com/content/8/7/32.full AB - Insulin resistance is emerging as a major contributor to cardiovascular risk, and the lipotoxicity that is associated with obesity is a key factor in the development of insulin resistance. Recent data that suggest that thiazolidinediones may provide some insight into this issue are reviewed in this article.