RT Journal Article SR Electronic A1 Cunningham, Muriel T1 Agomelatine Demonstrates Broad Efficacy in Depression JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 2 SP 15 OP 16 DO 10.1177/155989770700700208 UL http://mdc.sagepub.com/content/7/2/15.abstract AB Agomelatine, a melatonergic agonist and a selective 5-HT2c antagonist, is a novel antidepressant in development for major depressive disorder. This article discusses a meta-analysis of pooled data from three clinical studies. The objective of the meta-analysis was to determine whether gender or baseline severity of depression had any influence on agomelatine efficacy.