RT Journal Article SR Electronic A1 Jacobson, Anne T1 Prophylactic Cranial Irradiation in Extensive Disease Small Cell Lung Cancer JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 3 SP 13 OP 14 DO 10.1177/155989770700700306 UL http://mdc.sagepub.com/content/7/3/13.abstract AB Percutaneous cranial irradiation (PCI) has had benefit for patients with limited disease small cell lung cancer (SCLC). The findings of a study now indicate that PCI also has benefit in the setting of extensive disease-SCLC, where the risk of brain metastases is high. This article discusses the findings of a study in which PCI led to a significant reduction in the risk of symptomatic brain metastases and a significant prolongation of survival.