RT Journal Article SR Electronic A1 Helwick, Caroline T1 Cardiometabolic Risk Related to More than Insulin Resistance JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 6 SP 8 OP 8 DO 10.1177/155989770700700604 UL http://mdc.sagepub.com/content/7/6/8.abstract AB Results from the European Relationship Between Insulin Sensitivity and Cardiovascular Risk [RISC] study suggest that insulin resistance is not the sole underlying driver of cardiometabolic risk. Insulin exposure and obesity are also independent contributors. Furthermore, the lack of physical activity promotes the development of insulin resistance, and total activity of any kind (more than the intensity of the exercise) improves insulin sensitivity.