Summary

A substudy analysis within the COURAGE trial indicated that percutaneous coronary intervention (PCI) plus optimal medical therapy (OMT) led to significantly improved outcomes in patients with moderate-to-severe ischemia. The substudy results clarify the primary results of the COURAGE trial, reported earlier this year. The main trial results demonstrated that elective PCI plus OMT did not reduce death or MI compared with OMT alone for patients with stable coronary artery disease.