RT Journal Article SR Electronic T1 CHARISMA JF MD Conference Express YR 2006 FD SAGE Publications VO 6 IS 1 SP 12 OP 12 DO 10.1177/155989770601004 UL http://mdc.sagepub.com/content/6/1/12.abstract AB CHARISMA (Clopidogrel for High Atherothrombotic Risk, Ischemic Stabilization, Management, and Avoidance) is the first clinical trial to evaluate long-term effectiveness of clopidogrel plus aspirin in a population of high-risk patients, including symptomatic individuals with documented disease. Principal investigator Deepak Bhatt, MD, of the Cleveland Clinic Cardiovascular Coordinating Center, presented results from more than 15,000 study participants followed for a median of 2.3 years.