PT - JOURNAL ARTICLE ED - Bhatt, Deepak TI - CHARISMA DP - 2006 May 01 TA - MD Conference Express PG - 12--12 VI - 6 IP - 1 4099 - http://mdc.sagepub.com/content/6/1/12.short 4100 - http://mdc.sagepub.com/content/6/1/12.full AB - CHARISMA (Clopidogrel for High Atherothrombotic Risk, Ischemic Stabilization, Management, and Avoidance) is the first clinical trial to evaluate long-term effectiveness of clopidogrel plus aspirin in a population of high-risk patients, including symptomatic individuals with documented disease. Principal investigator Deepak Bhatt, MD, of the Cleveland Clinic Cardiovascular Coordinating Center, presented results from more than 15,000 study participants followed for a median of 2.3 years.