Summary

During the landmark Diabetes Control and Complications Trial [DCCT], physicians were concerned that episodes of hypoglycemia could adversely affect the brain and impair cognitive function. In this trial, subjects with type 1 diabetes were randomized to either an intensive treatment group or a conventional treatment arm. The fear was that by aggressively treating hyperglycemia, additional episodes of hypoglycemia would occur and have adverse consequences. This article gives an overview of the cognitive testing results from this cohort.