RT Journal Article SR Electronic A1 Vinall, Maria T1 The Clinical Efficacy and Safety of Subcutaneous Oral Application of Methotrexate in Patients with Active Rheumatoid Arthritis — Results of a Randomized, Controlled, Double-Blind, Multi-Center Study JF MD Conference Express YR 2006 FD SAGE Publications VO 6 IS 3 SP 16 OP 16 DO 10.1177/155989770600600311 UL http://mdc.sagepub.com/content/6/3/16.1.abstract AB Although oral MTX for the treatment of RA has been shown to be effective, adverse events may lead to discontinuation of treatment. This study reports the 24-week comparison of the safety and efficacy of subcutaneous (sc) vs orally administered MTX in patients with active RA.