PT - JOURNAL ARTICLE AU - O'Loughlin, Taryn ED - Dzavik, Vladimir TI - Results of the TOSCA-2 Trial: PCI Maintains Patency but has no Effect on LVEF DP - 2006 01 TA - MD Conference Express PG - 15--16 VI - 6 IP - 5 4099 - http://mdc.sagepub.com/content/6/5/15.2.short 4100 - http://mdc.sagepub.com/content/6/5/15.2.full AB - This article discusses the results of the Total Occlusion Study of Canada [TOSCA]-2, which was a mechanistic sub-study of the Occluded Artery Trial [OAT] funded by the National Institutes of Health. Observational studies have suggested beneficial effects of opening a persistently occluded infarct related artery so called “open artery hypothesis,” and the TOSCA-2 study set out to determine the effects of stent-based interventions 3 to 28 days post-myocardial infarction.