Evidence-Based AET in Women Before and After Menopause

Summary

The current evidence to guide adjuvant endocrine therapy in women with ER-positive breast cancer, including tamoxifen, aromatase inhibitors, and ovarian function suppression is reviewed. The studies include ATLAS, aTTom, SOFT, ECOG E3193, TEXT, ABCSG 12, and the Early Breast Cancer Trialists’ Collaborative Group meta-analysis.

  • premenopausal women
  • optimal treatment
  • postmenopausal women
  • mortality
  • overall survival
  • estrogen receptor-positive
  • tamoxifen
  • letrozole
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