RT Journal Article SR Electronic A1 Parry, Nicola T1 Advances in the Management of Retinoblastoma JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 43 SP 4 OP 6 DO 10.1177/155989771443001 UL http://mdc.sagepub.com/content/14/43/4.abstract AB There have been 4 periods in the history of retinoblastoma (Rb) since the 18th century: prehistologic, histologic, enucleation, and irradiation/chemotherapy. Since 1964, however, there has been an unprecedented rate of progress in research and treatment in Rb. This article discusses the advances that have occurred in Rb over the past 50 years.