RT Journal Article
SR Electronic
A1 Bittner, Dennis
T1 TRT in Addition to PCI Improves Outcomes for ES-SCLC
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 31
SP 9
OP 10
DO 10.1177/155989771431005
UL http://mdc.sagepub.com/content/14/31/9.2.abstract
AB Prophylactic cranial irradiation in the treatment of extensive-stage small cell lung cancer has proven value in reducing symptomatic brain metastases and in improving overall survival at 1 year. However, persistent intrathoracic disease occurs in 76% of such patients and intrathoracic disease progresses in almost 90% of this group. This article discusses data from the Chest Radiotherapy Extensive Stage Trial [CREST; NTR1527] that evaluated the use of thoracic radiotherapy in addition to PCI for treatment of ES-SCLC to prevent occurrence of thoracic disease and halt its progression.