Summary

The Stupp regimen of Hypofractionated radiotherapy (HRT) (Stupp regimen radiotherapy, SRT) is commonly used with temozolomide (T) for the treatment of elderly patients with glioblastoma (GBM). However, there has been insufficient study, and no randomized trials, comparing SRT with and without T to HRT. A retrospective study, discussed in this article, was designed to compare SRT and HRT alone and with T (SRT+T and HRT+T, respectively).