RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Phase 3 Trial to Compare Postoperative Chemotherapy with Observation in Stage I or II Endometrial Cancer
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 36
SP 20
OP 21
DO 10.1177/155989771436016
UL http://mdc.sagepub.com/content/14/36/20.abstract
AB Patients with stage I or II endometrial cancer are generally treated with surgery. Despite radical surgery, however, patients with medium- or high-risk stage I and II endometrial cancers are still at significant risk of local and distant progression. A current phase 3 study [NCT01244789] is preparing to evaluate whether survival can be improved in intermediate- and high-risk early-stage patients by offering postoperative chemotherapy instead of postoperative observation alone (standard strategy), as discussed in this article.