Phase 3 Trial to Compare Postoperative Chemotherapy with Observation in Stage I or II Endometrial Cancer

Summary

Patients with stage I or II endometrial cancer are generally treated with surgery. Despite radical surgery, however, patients with medium- or high-risk stage I and II endometrial cancers are still at significant risk of local and distant progression. A current phase 3 study [NCT01244789] is preparing to evaluate whether survival can be improved in intermediate- and high-risk early-stage patients by offering postoperative chemotherapy instead of postoperative observation alone (standard strategy), as discussed in this article.

  • Reproductive Cancers
  • Oncology Clinical Trials
  • Adjuvant/Neoadjuvant Therapy
  • Reproductive Cancers
  • Oncology Clinical Trials
  • Oncology
  • Adjuvant/Neoadjuvant Therapy
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