RT Journal Article
SR Electronic
A1 Parry, Nicola
T1 ERA 223 to Study Radium-223 and Abiraterone in Combination in mCRPC
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 36
SP 17
OP 18
DO 10.1177/155989771436013
UL http://mdc.sagepub.com/content/14/36/17.abstract
AB Skeletal metastases are common in prostate cancer, occurring in approximately 90% of men with advanced disease. Bone metastases result in decreased quality of life by causing problems such as bone pain, morbidity, pathologic fracture, and spinal cord compression. This article discusses the Phase III Randomized, Double-Blind, Placebo-Controlled Trial of Radium-223 Dichloride in Combination With Abiraterone Acetate and Prednisone/Prednisolone in the Treatment of Asymptomatic or Mildly Symptomatic Chemotherapy-Naïve Subjects With Bone Predominant Metastatic Castration-Resistant Prostate Cancer trial [ERA 223; NCT02043678].