RT Journal Article SR Electronic A1 Lederman, Lynne T1 Optimized and New Therapies Will Improve Prognosis in Patients with Advanced Prostate Cancer JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 14 SP 24 OP 26 DO 10.1177/155989771414015 UL http://mdc.sagepub.com/content/14/14/24.abstract AB The androgen receptor (AR) remains the most important target for metastatic castration-resistant prostate cancer (mCRPC). This article discusses new treatment modalities, including androgen synthesis inhibitors, chemotherapy, immunotherapy and radionuclide therapy.