RT Journal Article SR Electronic A1 Hoyle, Brian T1 COBI Can Substitute for RTV in an HIV-1 Drug Regimen JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 28 SP 18 OP 19 DO 10.1177/155989771428011 UL http://mdc.sagepub.com/content/14/28/18.abstract AB Week 144 secondary end point results from a randomized, double-blind, double-dummy, active-controlled study involving 700 treatment-naïve HIV-1-infected patients have reaffirmed that cobicistat can be substituted for ritonavir in a drug regimen that seeks to boost the pharmacologic effect of atazanavir in combination with emtricitabine-tenofovir disoproxil fumarate.