RT Journal Article
SR Electronic
A1 Gater, Laura
T1 GLP-1 — The New Darling of Diabetes Treatment
JF MD Conference Express
YR 2006
FD SAGE Publications
VO 6
IS 2
SP 9
OP 10
DO 10.1177/155989770600600202
UL http://mdc.sagepub.com/content/6/2/9.abstract
AB Glucagon-like peptide-1 (GLP-1) is an incretin hormone that regulates postprandial insulin secretion. The incretin effect is believed to be critical for maintenance of normal plasma glucose and glucose tolerance [Diab 1995]. Experiments using antagonists of the GLP-1 receptor show that GLP-1 is responsible for a substantial part of the insulin response to oral glucose [Diab 1995; Diab 1994]. This article discusses GLP-1 receptor agonists and DPP IV inhibitors.