PT - JOURNAL ARTICLE AU - Gater, Laura ED - Nauck, Michael TI - GLP-1 — The New Darling of Diabetes Treatment DP - 2006 Sep 01 TA - MD Conference Express PG - 9--10 VI - 6 IP - 2 4099 - http://mdc.sagepub.com/content/6/2/9.short 4100 - http://mdc.sagepub.com/content/6/2/9.full AB - Glucagon-like peptide-1 (GLP-1) is an incretin hormone that regulates postprandial insulin secretion. The incretin effect is believed to be critical for maintenance of normal plasma glucose and glucose tolerance [Diab 1995]. Experiments using antagonists of the GLP-1 receptor show that GLP-1 is responsible for a substantial part of the insulin response to oral glucose [Diab 1995; Diab 1994]. This article discusses GLP-1 receptor agonists and DPP IV inhibitors.