RT Journal Article SR Electronic A1 Gater, Laura T1 IL-1 Receptor Antagonist Therapy in Type 2 Diabetes JF MD Conference Express YR 2006 FD SAGE Publications VO 6 IS 2 SP 14 OP 14 DO 10.1177/155989770600600206 UL http://mdc.sagepub.com/content/6/2/14.abstract AB Impaired β-cell function and decreased β-cell mass due to apoptosis contribute to impaired insulin secretion in patients with type 2 diabetes. Interleukin-1 receptor antagonists (IL-1Ra) can block β-cell apoptosis, and patients with type 2 diabetes are known to have reduced levels of IL-1Ra expression. This article presents results from a recent study examining anakinra in the treatment of type 2 diabetes.