RT Journal Article
SR Electronic
A1 Cunningham, Muriel
T1 Tamoxifen Treatment of Bipolar Disorder
JF MD Conference Express
YR 2007
FD SAGE Publications
VO 7
IS 2
SP 32
OP 33
DO 10.1177/155989770700700216
UL http://mdc.sagepub.com/content/7/2/32.abstract
AB Protein kinase C (PKC) is a family of enzymes involved in phosphorylation and cellular messaging. A growing body of evidence suggests that PKC inhibition may be a possible mechanism to treat bipolar disorder. Tamoxifen, an antiestrogen used in breast cancer treatment, is currently the only PKC inhibitor capable of penetrating the central nervous system.