PT  - JOURNAL ARTICLE
ED  - Creager, Mark
ED  - Diaz, Raphael
ED  - Schneider, David J.
ED  - Nesto, Richard
ED  - Connolly, Mark
TI  - Metabolic Management of the Patient with Ischemic Heart Disease: Diabetes and Metabolic Syndrome
DP  - 2006 May 01
TA  - MD Conference Express
PG  - 29--29
VI  - 6
IP  - 1
4099  - http://mdc.sagepub.com/content/6/1/29.short
4100  - http://mdc.sagepub.com/content/6/1/29.full
AB  - “Let's get one thing clear,” said Mark Creager, MD, Harvard Medical School. “Diabetes is a cardiovascular disorder.” Dr. Creager reviewed links between hyperglycemia and endothelial dysfunction, including the interplay of free fatty acids that increase oxidative stress. “Hyperglycemia activates signaling events at the endothelial level we'd just as soon never got started,” he said. “Ultimately, hyperglycemia has a direct effect on thrombosis and fibrinolysis.”