RT Journal Article
SR Electronic
A1 Hoyle, Brian
T1 Mutational Signatures in Human Cancer
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 36
SP 4
OP 5
DO 10.1177/155989771436001
UL http://mdc.sagepub.com/content/14/36/4.abstract
AB To date, 10 000 to 20 000 cancer genomes have been fully or partially sequenced. Cancer genome sequences could prove crucial in predicting therapy outcome and response and could allow the development of assays that detect sequence fragments that leak out of cancer cells. It is hoped that these fragments will prove to be diagnostic hallmarks. This article discusses the mutational signatures of human cancer.