New Tools, Pathways, and Challenges That Address the Crisis of Antimicrobial Resistance

Article Figures & Data

Figures

  • Figure 1.

    Number of New Antibiotics Developed Over the Past 30 Years

    Reprinted from Clin Infect Dis, Boucher HW et al, 10 × 20 Progress—Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America, 2013;56(12):1685–1694, Copyright 2013, with permission from Infectious Diseases Society of America.
  • Figure 2.

    Trial Designs Using Pathogen-Focused Pathways

    Reprinted from Lancet Infect Dis, 13, Rex JH et al, A comprehensive regulatory framework to address the unmet need for new antibacterial treatments, 269–75, Copyright 2013, with permission from Elsevier.
  • Figure 3.

    Timeline for New Antibiotic Development

    FDA, Food and Drug Administration. aHit to phase 2 based on novel mechanism antibiotic discovery.Adapted from Paul SM et al. Nat Rev Drug Discov. 2010.