Impact of Early Adequate Antimicrobials in Septic Shock
Reproduced from Nobre V et al. Prompt antibiotic administration and goal-directed hemodynamic support in patients with severe sepsis and septic shock. Curr Opin Crit Care. 2007;13:586–591. As adapted from Kumar A et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589–1596. Used with permission from Lippincott Williams & Wilkins.