RT Journal Article
SR Electronic
A1 Zarifyan, Alla
T1 PATHWAY-2 and -3
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 15
IS 28
SP 12
OP 13
DO 10.1177/1559897715611371
UL http://mdc.sagepub.com/content/15/28/12.abstract
AB PATHWAY-2 and PATHWAY-3 demonstrated that potassium-sparing diuretics are safe and effective for the treatment of hypertension. Spironolactone was significantly more effective in controlling resistant hypertension than doxazosin or bisoprolol, whereas the amiloride/HCTZ combination neutralized the undesirable changes in blood glucose and potassium while significantly lowering blood pressure.