RT Journal Article
SR Electronic
A1 Lederman, Lynne
T1 MSCs Do Not Reduce Time to Recovery in Postcardiopulmonary Bypass AKI
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 14
IS 49
SP 12
OP 13
DO 10.1177/155989771449007
UL http://mdc.sagepub.com/content/14/49/12.2.abstract
AB Acute kidney injury (AKI) is a major complication of cardiac surgery and can progress to chronic kidney disease and death. Allogeneic mesenchymal stem cells (MSCs) have been shown to reduce the severity of and improve the recovery from AKI in preclinical studies. This article discusses A Study to Evaluate the Safety and Efficacy of AC607 for the Treatment of Kidney Injury in Cardiac Surgery Subjects [NCT01602328], which compared the time to kidney recovery with AC607 vs placebo in the setting of postcardiac surgery.