RT Journal Article SR Electronic A1 Summers, Jaye T1 Late-Breaking Topics in Clinical Nutrition JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 3 SP 6 OP 8 DO 10.1177/1559897715579634 UL http://mdc.sagepub.com/content/15/3/6.abstract AB In critically ill patients, the CALORIES trial showed no significant difference between 2 feeding methods on all-cause mortality; the MetaPlus trial results suggest no benefit from administration of an immune-enhanced enteral formula; in the TARGET trial, a higher-density enteral formula led to higher daily caloric intakes; and results from the ICU Microbiome Project indicate that loss of microbiome diversity may lead to poor clinical outcomes.