RT Journal Article SR Electronic A1 Zarifyan, Alla T1 MR CLEAN: TOR Affects Treatment Efficacy in Patients With Acute Ischemic Stroke JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 2 SP 12 OP 12 DO 10.1177/1559897715578108 UL http://mdc.sagepub.com/content/15/2/12.2.abstract AB An analysis of the MR CLEAN trial demonstrated a significant interaction between time from stroke onset to reperfusion and treatment effect, with the decrease in absolute risk difference between treated and untreated patients of almost 7% per hour (Pā€‰=ā€‰.038). The relationship between time to treatment and treatment effect was not statistically significant but is still considered biologically plausible.