PT - JOURNAL ARTICLE AU - Zarifyan, Alla ED - Fransen, Puck TI - MR CLEAN: TOR Affects Treatment Efficacy in Patients With Acute Ischemic Stroke DP - 2015 Apr 01 TA - MD Conference Express PG - 12--12 VI - 15 IP - 2 4099 - http://mdc.sagepub.com/content/15/2/12.2.short 4100 - http://mdc.sagepub.com/content/15/2/12.2.full AB - An analysis of the MR CLEAN trial demonstrated a significant interaction between time from stroke onset to reperfusion and treatment effect, with the decrease in absolute risk difference between treated and untreated patients of almost 7% per hour (Pā€‰=ā€‰.038). The relationship between time to treatment and treatment effect was not statistically significant but is still considered biologically plausible.