LEGACY

Summary

Weight loss in patients with atrial fibrillation and a body mass index > 27 kg/m is associated with dose-dependent improved control of sinus rhythm and lower atrial fibrillation burden, according to the 5-year LEGACY study. However, > 5% weight fluctuation can offset these benefits.

  • obesity
  • atrial fibrillation
  • antiarrhythmic drugs
  • ablation
  • weight loss
  • LEGACY
  • ACTRN12614001123639
  • cardiology & cardiovascular medicine clinical trials
  • arrhythmias
  • cardiometabolic disorder
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