RT Journal Article SR Electronic A1 Summers, Jaye T1 REFLEXION Trial JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 9 SP 14 OP 15 DO 10.1177/1559897715588491 UL http://mdc.sagepub.com/content/15/9/14.2.abstract AB Many who experience a first demyelinating clinical event will convert to clinically definite multiple sclerosis. Data from the REFLEX and REFLEXION trials suggest that patients who receive early treatment with interferon beta 1-a will convert to multiple sclerosis later than patients who took placebo prior to receiving interferon beta 1-a.