RT Journal Article SR Electronic A1 Parry, Nicola T1 MR CLEAN JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 9 SP 7 OP 8 DO 10.1177/1559897715588318 UL http://mdc.sagepub.com/content/15/9/7.2.abstract AB The MR CLEAN trial evaluates the effect of intra-arterial intervention in proximal anterior circulation acute ischemic stroke. Endovascular therapy within 6 hours of onset improves functional outcomes compared with standard guideline stroke treatment. Intervention is beneficial, in particular, to patients older than 80 years and those in the lower modified NIH Stroke Scale categories.