RT Journal Article SR Electronic A1 Mosley, Mary T1 Strategies for Optimizing Radiation Therapy for Small Cell Lung Cancer JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 8 SP 23 OP 24 DO 10.1177/1559897715588458 UL http://mdc.sagepub.com/content/15/8/23.abstract AB The current evidence for the optimal delivery of radiation therapy in patients with small cell lung cancer is reviewed in this article. Hippocampal avoidance prophylactic cranial irradiation is being studied to reduce the associated neurocognitive deficits. Thoracic radiation therapy combined with prophylactic cranial irradiation was shown to improve overall survival and progression-free survival and reduce intrathoracic progression in the CREST trial.