Summary
ALTER0302, a randomized double-blind controlled phase 2 trial, examined the efficacy and safety of anlotinib, a multitargeted tyrosine kinase inhibitor, as third-line therapy for Chinese patients with advanced non–small cell lung cancer. Progression-free survival and objective response rates were increased in all subgroups of patients treated with anlotinib with no associated serious adverse events.
- non–small cell lung cancer
- refractory advanced non–small cell lung cancer
- anlotinib
- progression-free survival
- NCT01924195
- ALTER0302
- third-line chemotherapy
- oncology clinical trials
- © 2015 SAGE Publications