RT Journal Article SR Electronic A1 Rizzo, Toni T1 Novel Approaches to the Treatment of Osteoporosis JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 4 SP 19 OP 22 DO 10.1177/1559897715581827 UL http://mdc.sagepub.com/content/15/4/19.abstract AB The 2 currently available categories of osteoporosis therapies are the antiresorptive agents, which decrease bone resorption and bone formation, and parathyroid hormone agonists, which increase bone formation and bone resorption. Cathepsin K inhibition is a new mechanism of action that inhibits bone resorption while preserving bone formation.