RT Journal Article SR Electronic A1 Boltz, Kathy T1 Biochemical Control of Acromegaly Continued in PAOLA Trial Extension JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 4 SP 10 OP 10 DO 10.1177/1559897715583811 UL http://mdc.sagepub.com/content/15/4/10.2.abstract AB This extension study of the phase 3 PAOLA trial found that pasireotide LAR may be a viable, long-term treatment option for patients with acromegaly that is inadequately controlled with first-generation somatostatin analogues. Biochemical control of growth hormone and normalized insulin-like growth factor 1 continued through extension week 28.