RT Journal Article SR Electronic A1 Boltz, Kathy T1 The PAOLA Study JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 4 SP 8 OP 10 DO 10.1177/1559897715582168 UL http://mdc.sagepub.com/content/15/4/8.2.abstract AB Pasireotide LAR had a dose-proportional relationship with dose exposure over a 40- to 60-mg range. Efficacy end points of levels of growth hormone and IGF-1 were correlated with pasireotide exposure, and response rates were higher at the higher pasireotide dose.