RT Journal Article SR Electronic A1 Boltz, Kathy T1 Cariprazine Leads to Clinically Meaningful Improvements in Bipolar Symptoms JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 11 SP 4 OP 5 DO 10.1177/1559897715593506 UL http://mdc.sagepub.com/content/15/11/4.abstract AB Cariprazine treatment results in clinically meaningful improvements across a broad spectrum of bipolar mania symptoms. Symptom severity shifted from moderate or worse to mild or no symptoms after 3 weeks of cariprazine treatment. Significantly more patients achieve remission with cariprazine vs placebo.