PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Reau, Nancy S. ED - Naggie, Susanna TI - New Treatment Paradigm for HCV and HCV/HIV Coinfection DP - 2015 Sep 07 TA - MD Conference Express PG - 25--27 VI - 15 IP - 14 4099 - http://mdc.sagepub.com/content/15/14/25.short 4100 - http://mdc.sagepub.com/content/15/14/25.full AB - New treatment regimens utilizing combinations of protease (nonstructural protein 3-4A [NS3-4A]), nucleotide (NS5B), nonnucleoside (NS5B), and NS5A inhibitors are successfully being used to treat patients with hepatitis C virus coinfected with HIV. Sustained virologic response rates of ≥ 90% are achieved after 12 to 24 weeks in patients with and without cirrhosis who are treatment naïve and experienced. HIV is no longer a predictor of poorer response to hepatitis C virus therapy.