RT Journal Article
SR Electronic
A1 Summers, Jaye
T1 Simeprevir + Sofosbuvir Effective in Patients With Moderate to Severe Cirrhosis
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 15
IS 14
SP 18
OP 19
DO 10.1177/1559897715593931
UL http://mdc.sagepub.com/content/15/14/18.abstract
AB There are few data regarding the efficacy and safety of simeprevir + sofosbuvir in patients with decompensated cirrhosis. Data from this study comparing this drug combination in patients with Child-Pugh B/C cirrhosis with patients who received older treatment regimens suggest that recently approved all-oral therapies offer patients with decompensated cirrhosis a safer and more effective therapy than historical peginterferon-based therapies.