RT Journal Article SR Electronic A1 Summers, Jaye T1 IBREST Trial JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 14 SP 17 OP 18 DO 10.1177/1559897715593898 UL http://mdc.sagepub.com/content/15/14/17.abstract AB In the IBREST trial, when compared with placebo, a novel targeted delivery system of peppermint oil is more effective in treating symptoms of nonconstipated irritable bowel syndrome at 4 weeks. The trial shows significant improvement in the Total IBS Symptoms Score and 4 of 8 symptom domains. Furthermore, the treatment appears safe and well tolerated.