PT - JOURNAL ARTICLE AU - Lederman, Lynne ED - Chey, William D. TI - Eluxadoline Shows Efficacy for IBS-D in IBS3001 and IBS3002 Phase 3 Trials DP - 2015 Sep 07 TA - MD Conference Express PG - 12--13 VI - 15 IP - 14 4099 - http://mdc.sagepub.com/content/15/14/12.2.short 4100 - http://mdc.sagepub.com/content/15/14/12.2.full AB - Eluxadoline, a ยต-opioid receptor agonist and d-opioid receptor antagonist, exhibits rapid onset of action along with sustained efficacy over the 6-month treatment period as studied in the phase 3, double-blind, placebo-controlled IBS3001 and IBS3002 trials in patients with diarrhea-predominant irritable bowel syndrome.