RT Journal Article
SR Electronic
A1 Summers, Jaye
T1 Analysis of SVR Rates Across Populations With Multiple Negative Predictors
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 15
IS 14
SP 8
OP 9
DO 10.1177/1559897715593919
UL http://mdc.sagepub.com/content/15/14/8.abstract
AB Multivariate analysis shows that > 2000 patients with hepatitis C virus who received 3 direct-acting antivirals and had <4 predictors of negative response experienced 12-week sustained virologic response rates > 95%. Analysis of those that received the label-recommended regimen found that the only 2 negative predictors associated with significantly lower response rates are obesity and genotype 1a disease. Even those with both factors achieved sustained virologic response rates of 95% at week 12.