RT Journal Article
SR Electronic
A1 Shuman, Jill
T1 Management of Posttraumatic Bleeding and Trauma-Induced Coagulopathy
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 15
IS 21
SP 22
OP 23
DO 10.1177/1559897715599522
UL http://mdc.sagepub.com/content/15/21/22.abstract
AB Data from the CRASH-2 trial showed that tranexamic acid significantly reduced mortality in trauma patients, but no harm was detected. It is most effective when tranexamic acid is administered within 3 hours of the initial traumatic event. The TACTIC collaboration is currently conducting multiple preclinical and clinical studies to better manage posttraumatic hemorrhage.