RT Journal Article SR Electronic A1 Hoyle, Brian T1 Advances in Treatment of Acute Ischemic Stroke JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 21 SP 14 OP 14 DO 10.1177/1559897715599371 UL http://mdc.sagepub.com/content/15/21/14.2.abstract AB Acute ischemic stroke is the leading cause of disability and the third-most common cause of death in the developed world. Time to treatment is crucial. Intravenous administration of tissue plasminogen activator within 3 hours of stroke is very effective. Developments in mechanical thrombectomy have made it an appealing treatment option.