PT - JOURNAL ARTICLE AU - Hoyle, Brian ED - van Adel, Brian TI - Advances in Treatment of Acute Ischemic Stroke DP - 2015 Sep 10 TA - MD Conference Express PG - 14--14 VI - 15 IP - 21 4099 - http://mdc.sagepub.com/content/15/21/14.2.short 4100 - http://mdc.sagepub.com/content/15/21/14.2.full AB - Acute ischemic stroke is the leading cause of disability and the third-most common cause of death in the developed world. Time to treatment is crucial. Intravenous administration of tissue plasminogen activator within 3 hours of stroke is very effective. Developments in mechanical thrombectomy have made it an appealing treatment option.